Fulton County police said just after 9 p.m. Thursday, the men forced their way into a home on Polar Fox Court.
Authorities said the men duct-taped the victims and robbed them.
A teenager and a young boy jumped from a second-floor window to escape, police said. They are OK.
The family said they had thousands of dollars in the home.
Its income tax money. We think it was an inside friend who told this information, said family member Robin Glenn.
The men were last seen on Old National Highway.